Publications
2020
Mena
Ani,
Noha
Elemam,
Jennifer
Hundt, and
Azzam
Maghazachi,
Drugs for Multiple Sclerosis Activate Natural Killer Cells: Do They Protect Against COVID-19 Infection?, Infection and Drug Resistance , vol. 2020, pp. 3243—3254, 09 2020.
Drugs for Multiple Sclerosis Activate Natural Killer Cells: Do They Protect Against COVID-19 Infection?, Infection and Drug Resistance , vol. 2020, pp. 3243—3254, 09 2020.
DOI: | 10.2147/IDR.S269797 |
Shifaa
Abdin,
Mai
Tolba,
Dana
Zaher, and
Hany
Omar,
Abstract 4107: The impact of NF-κB inhibition on the sensitivity of breast cancer cells to chemotherapy-induced apoptosis, 082020. pp. 4107-4107.
Abstract 4107: The impact of NF-κB inhibition on the sensitivity of breast cancer cells to chemotherapy-induced apoptosis, 082020. pp. 4107-4107.
DOI: | 10.1158/1538-7445.AM2020-4107 |
Israa
Shihab,
Bariaa
Khalil,
Noha
Elemam,
Ibrahim
Hachim,
Mahmood
Hachim,
Rifat
Hamoudi, and
Azzam
Maghazachi,
Understanding the Role of Innate Immune Cells and Identifying Genes in Breast Cancer Microenvironment, Cancers , vol. 12, pp. 2226, 08 2020.
Understanding the Role of Innate Immune Cells and Identifying Genes in Breast Cancer Microenvironment, Cancers , vol. 12, pp. 2226, 08 2020.
DOI: | 10.3390/cancers12082226 |
Iman
Talaat,
Wafaa
Ramadan,
Mahmood
Hachim,
Ibrahim
Hachim,
Nada
Yakout,
Dua'A
Alnusairat, and
Wael
Abdel-Rahman,
Differential Expression of Insulin‐Like Growth Factor‐1 Receptor in Breast Cancer Subtypes: A Marker of Early Metastasis in HER‐2 Subtype, The FASEB Journal , vol. 34, pp. 1-1, 04 2020.
Differential Expression of Insulin‐Like Growth Factor‐1 Receptor in Breast Cancer Subtypes: A Marker of Early Metastasis in HER‐2 Subtype, The FASEB Journal , vol. 34, pp. 1-1, 04 2020.
DOI: | 10.1096/fasebj.2020.34.s1.02830 |
Dana
Zaher,
Mohammed
El-Gamal,
Hany
Omar,
Sarah
Aljareh,
Salma
Alshamma,
Aya
Ali,
Sumera
Zaib, and
Jamshed
Iqbal,
Recent advances with alkaline phosphatase isoenzymes and their inhibitors, Archiv der Pharmazie , vol. 353, 03 2020.
Recent advances with alkaline phosphatase isoenzymes and their inhibitors, Archiv der Pharmazie , vol. 353, 03 2020.
DOI: | 10.1002/ardp.202000011 |
El-Shaimaa
Arafa,
Wafaa
Mohamed,
Dana
Zaher, and
Hany
Omar,
Gliclazide attenuates acetic acid-induced colitis via the modulation of PPARγ, NF-κB and MAPK signaling pathways, Toxicology and Applied Pharmacology , vol. 391, pp. 114919, 02 2020.
Gliclazide attenuates acetic acid-induced colitis via the modulation of PPARγ, NF-κB and MAPK signaling pathways, Toxicology and Applied Pharmacology , vol. 391, pp. 114919, 02 2020.
DOI: | 10.1016/j.taap.2020.114919 |
Mahmood
Hachim,
Bariaa
Khalil,
Noha
Elemam, and
Azzam
Maghazachi,
Pyroptosis: The missing puzzle among innate and adaptive immunity crosstalk, Journal of Leukocyte Biology , vol. 108, 02 2020.
Pyroptosis: The missing puzzle among innate and adaptive immunity crosstalk, Journal of Leukocyte Biology , vol. 108, 02 2020.
DOI: | 10.1002/JLB.3MIR0120-625R |
Fatema
Hersi,
Hany
Omar,
Raed
al-qawasmeh,
Zainab
Ahmad,
Areej
Jaber,
Dana
Zaher, and
Taleb
Al-Tel,
Design and synthesis of new energy restriction mimetic agents: Potent anti-tumor activities of hybrid motifs of aminothiazoles and coumarins, Scientific Reports , vol. 10, 02 2020.
Design and synthesis of new energy restriction mimetic agents: Potent anti-tumor activities of hybrid motifs of aminothiazoles and coumarins, Scientific Reports , vol. 10, 02 2020.
DOI: | 10.1038/s41598-020-59685-x |
Shahira
el-menshawe,
Ossama
Sayed,
Heba
Abou-Taleb,
Mina
Saweris,
Dana
Zaher, and
Hany
Omar,
The use of new quinazolinone derivative and doxorubicin loaded solid lipid nanoparticles in reversing drug resistance in experimental cancer cell lines: A systematic study, Journal of Drug Delivery Science and Technology , vol. 56, pp. 101569, 02 2020.
The use of new quinazolinone derivative and doxorubicin loaded solid lipid nanoparticles in reversing drug resistance in experimental cancer cell lines: A systematic study, Journal of Drug Delivery Science and Technology , vol. 56, pp. 101569, 02 2020.
DOI: | 10.1016/j.jddst.2020.101569 |
Wafaa
Ramadan,
Dana
Zaher,
Alaa
Altaie,
Iman
Talaat, and
Adel
Elmoselhi,
Potential Therapeutic Strategies for Lung and Breast Cancers through Understanding the Anti- Angiogenesis Resistance Mechanisms, International Journal of Molecular Sciences , vol. 21, 01 2020.
Potential Therapeutic Strategies for Lung and Breast Cancers through Understanding the Anti- Angiogenesis Resistance Mechanisms, International Journal of Molecular Sciences , vol. 21, 01 2020.
DOI: | 10.3390/ijms21020565 |
Mahmood Y.
Hachim,
Bariaa A.
Khalil,
Noha M.
Elemam, and
Azzam A.
Maghazachi,
Pyroptosis: The missing puzzle among innate and adaptive immunity crosstalk, Journal of Leukocyte Biology , vol. 108, no. 1, pp. 323-338, 2020.
Pyroptosis: The missing puzzle among innate and adaptive immunity crosstalk, Journal of Leukocyte Biology , vol. 108, no. 1, pp. 323-338, 2020.
DOI: | https://doi.org/10.1002/JLB.3MIR0120-625R |
File: | JLB.3MIR0120-625R |
Fatemeh
Saheb Sharif-Askari,
Narjes
Saheb Sharif-Askari,
Swati
Goel,
Samer
Fakhri,
Saleh
Al-Muhsen,
Qutayba
Hamid, and
Rabih
Halwani,
Are patients with chronic rhinosinusitis with nasal polyps at a decreased risk of COVID-19 infection?, International Forum of Allergy \& Rhinology , vol. 10, no. 10, pp. 1182-1185, 2020.
Are patients with chronic rhinosinusitis with nasal polyps at a decreased risk of COVID-19 infection?, International Forum of Allergy \& Rhinology , vol. 10, no. 10, pp. 1182-1185, 2020.
DOI: | https://doi.org/10.1002/alr.22672 |
File: | alr.22672 |
Maha
Saber-Ayad,
Sarah
Hammoudeh,
Hadia
Radwan,
Shaista
Manzoor,
Hussein
Jabbar,
Rahaf
Wardeh,
Ahmed
Ashraf,
Peter
Habib,
Alsamman M.
Alsamman, and
Rifat
Hamoudi,
The FGF-21 genetic variants rs838133 and rs838145 are associated with high salt intake in the Emirati population, Journal of Advanced Research , vol. 24, pp. 485-494, 2020.
The FGF-21 genetic variants rs838133 and rs838145 are associated with high salt intake in the Emirati population, Journal of Advanced Research , vol. 24, pp. 485-494, 2020.
DOI: | https://doi.org/10.1016/j.jare.2020.05.020 |
File: | S209012322030103X |
2019
Maha
Saber-Ayad,
Shaista
Manzoor,
Hadia
Radwan,
Sarah
Hammoudeh,
Rahaf
Wardeh,
Ahmed
Ashraf,
Hussein
Jabbar, and
Rifat
Hamoudi,
The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population, PLOS ONE , vol. 14, Oct. 2019.
The FTO genetic variants are associated with dietary intake and body mass index amongst Emirati population, PLOS ONE , vol. 14, Oct. 2019.
DOI: | 10.1371/journal.pone.0223808 |
Srinivasulu
Vunnam,
Monther
Khanfar,
Hany
Omar,
Raafat
ElAwady,
Scott
Sieburth,
Anusha
Sebastian,
Dana
Zaher,
Farah
Al-Marzooq,
Fatema
Hersi, and
Taleb
Al-Tel,
Sequencing [4+1]-Cycloaddition and Aza-Michael Addition Reactions: A Diastereoselective Cascade for the Rapid Access of Pyrido[2',1':2,3]/Thiazolo[2',3':2,3]imidazo[1,5-a]quinolone Scaffolds as Potential Antibacterial and Anticancer Motifs, The Journal of Organic Chemistry , vol. 2019, Oct. 2019.
Sequencing [4+1]-Cycloaddition and Aza-Michael Addition Reactions: A Diastereoselective Cascade for the Rapid Access of Pyrido[2',1':2,3]/Thiazolo[2',3':2,3]imidazo[1,5-a]quinolone Scaffolds as Potential Antibacterial and Anticancer Motifs, The Journal of Organic Chemistry , vol. 2019, Oct. 2019.
DOI: | 10.1021/acs.joc.9b01919 |
Cijo
Vazhappilly,
Shabbir
Ansari,
Rula
Al-Jaleeli,
Aya
Al-Azawi,
Wafaa
Ramadan,
Varsha
Menon,
Rawad
Hodeify,
Shoib
Siddiqui,
Maxime
Merheb,
Rachel
Matar, and
Rajan
Radhakrishnan,
Role of flavonoids in thrombotic, cardiovascular, and inflammatory diseases, Inflammopharmacology , vol. 27, Oct. 2019.
Role of flavonoids in thrombotic, cardiovascular, and inflammatory diseases, Inflammopharmacology , vol. 27, Oct. 2019.
DOI: | 10.1007/s10787-019-00612-6 |
Hayat
Jaibeji,
Debasmita
Mukhopadhyay,
Abdul khader
Mohammed,
Sarah
Dhaiban,
Mahmood
Hachim,
Noha
Elemam,
Nabil
Sulaiman,
Albert
Salehi, and
Jalal
Taneera,
Reduced Expression of PLCXD3 Associates With Disruption of Glucose Sensing and Insulin Signaling in Pancreatic β-Cells, Frontiers in Endocrinology , vol. 10, pp. 735, Oct. 2019.
Reduced Expression of PLCXD3 Associates With Disruption of Glucose Sensing and Insulin Signaling in Pancreatic β-Cells, Frontiers in Endocrinology , vol. 10, pp. 735, Oct. 2019.
DOI: | 10.3389/fendo.2019.00735 |
Jalal
Taneera,
Israa
Mohamed,
Abdul khader
Mohammed,
Mahmood
Hachim,
Sarah
Dhaiban,
Abdullah
Malek,
Pontus
Dunér,
Noha
Elemam,
Nabil
Sulaiman,
Mawieh
Hamad, and
Albert
Salehi,
Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced β-cell dysfunction, Molecular and Cellular Endocrinology , vol. 499, pp. 110592, 09 2019.
Orphan G-protein coupled receptor 183 (GPR183) potentiates insulin secretion and prevents glucotoxicity-induced β-cell dysfunction, Molecular and Cellular Endocrinology , vol. 499, pp. 110592, 09 2019.
DOI: | 10.1016/j.mce.2019.110592 |
Jalal
Taneera,
Sarah
Dhaiban,
Mahmood
Hachim,
Abdul khader
Mohammed,
Debasmita
Mukhopadhyay,
Khuloud
Bajbouj,
Rifat
Hamoudi,
Albert
Salehi,
Mawieh
Hamad, and
Affiliations,
Reduced Expression of Chl1 gene Impairs Insulin Secretion by Down-Regulating the Expression of Key Molecules of β-cell Function, Experimental and clinical endocrinology , pp. 1-9, 09 2019.
Reduced Expression of Chl1 gene Impairs Insulin Secretion by Down-Regulating the Expression of Key Molecules of β-cell Function, Experimental and clinical endocrinology , pp. 1-9, 09 2019.
DOI: | 10.1055/a-1014-2544 |
Hany
Omar,
Ahmed
El-Serafi,
Fatema
Hersi,
El-Shaimaa
Arafa,
Dana
Zaher,
Mohamed
Madkour,
Hany
Arab, and
Mai
Tolba,
Immunomodulatory MicroRNAs in Cancer: Targeting Immune Checkpoints and the Tumor Microenvironment, FEBS Journal , 07 2019.
Immunomodulatory MicroRNAs in Cancer: Targeting Immune Checkpoints and the Tumor Microenvironment, FEBS Journal , 07 2019.
DOI: | 10.1111/febs.15000 |
Sarah
Hammoudeh,
Arabella
Hammoudeh, and
Rifat
Hamoudi,
High-throughput quantification of the effect of DMSO on the viability of lung and breast cancer cells using an easy-to-use spectrophotometric trypan blue-based assay, Histochemistry and Cell Biology , vol. 152, 07 2019.
High-throughput quantification of the effect of DMSO on the viability of lung and breast cancer cells using an easy-to-use spectrophotometric trypan blue-based assay, Histochemistry and Cell Biology , vol. 152, 07 2019.
DOI: | 10.1007/s00418-019-01775-7 |
Mohammed
El-Gamal,
Saif
Ullah,
Sayed
Zaraie,
Saquib
Jalil,
Sumera
Zaib,
Dana
Zaher,
Hany
Omar,
H.s
Anbar,
Julie
Pelletier,
Jean
Sévigny, and
Jamshed
Iqbal,
Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase, European Journal of Medicinal Chemistry , vol. 181, 07 2019.
Synthesis, biological evaluation, and docking studies of new raloxifene sulfonate or sulfamate derivatives as inhibitors of nucleotide pyrophosphatase/phosphodiesterase, European Journal of Medicinal Chemistry , vol. 181, 07 2019.
DOI: | 10.1016/j.ejmech.2019.07.063 |
Jalal
Taneera,
Sarah
Dhaiban,
Abdul khader
Mohammed,
Debasmita
Mukhopadhyay,
Hayat
Jaibeji,
Nabil
Sulaiman,
João
Fadista, and
Albert
Salehi,
GNAS gene is an important regulator of insulin secretory capacity in pancreatic β-cells, Gene , vol. 715, pp. 144028, 07 2019.
GNAS gene is an important regulator of insulin secretory capacity in pancreatic β-cells, Gene , vol. 715, pp. 144028, 07 2019.
DOI: | 10.1016/j.gene.2019.144028 |
Khaled
Abdellatif,
Wael
Fadaly,
Yaser
Mostafa,
Dana
Zaher, and
Hany
Omar,
Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities, Bioorganic Chemistry , vol. 91, pp. 103132, 07 2019.
Thiohydantoin derivatives incorporating a pyrazole core: Design, synthesis and biological evaluation as dual inhibitors of topoisomerase-I and cycloxygenase-2 with anti-cancer and anti-inflammatory activities, Bioorganic Chemistry , vol. 91, pp. 103132, 07 2019.
DOI: | 10.1016/j.bioorg.2019.103132 |
Cijo
Vazhappilly,
Ekram
Saleh,
Wafaa
Ramadan,
Varsha
Menon,
Aya
Al-Azawi,
Hamadeh
Tarazi,
Hajjaj
Abdu-allah,
Abdel-Nasser
El-Shorbagi, and
Raafat
el-awady,
Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types, Investigational New Drugs , vol. 37, pp. 1-10, 04 2019.
Inhibition of SHP2 by new compounds induces differential effects on RAS/RAF/ERK and PI3K/AKT pathways in different cancer cell types, Investigational New Drugs , vol. 37, pp. 1-10, 04 2019.
DOI: | 10.1007/s10637-018-0626-5 |